DUOBRII Lotion for Plaque Psoriasis

This shop has been compensated by Inmar, Inc. and Ortho Dermatologics. I am working with the makers of DUOBRII® (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, in 2021. All opinions are mine alone. DUOBRII Lotion should not be used during pregnancy. Individual results may vary. Available by prescription only. #ad #TryDuobrii #DUOBRII

My husband Chad really struggles with plaque psoriasis and I am really looking forward to him trying DUOBRII Lotion from Ortho Dermatologics to see if it will help! Whenever we go swimming or to the beach, he covers up in long sleeve shirts, so it would be great if he could feel comfortable again!

I have been researching the benefits of DUOBRII Lotion and I learned that it is made of two well-known ingredients that work together to treat plaque psoriasis in adults, while each ingredient reduces the side effects of the other. The strong anti-inflammatory agent (halobetasol propionate) works to clear plaques, while tazarotene (a Vitamin A derivative), helps extend the clearing process even after stopping treatment. I was excited to learn that over 40% of patients had clear or almost clear skin in 8 weeks or less in 2 clinical studies. AND one third of patients were still clear one month after stopping treatment! Chad is excited to talk to his doctor about a prescription.

Important Note:

It’s important to note that DUOBRII Lotion should be applied once a day, only until your psoriasis is under control. All other potent-to-superpotent steroids have time limits on dosing. Talk to your doctor if you experience side effects. Click here to learn more!

DUOBRII Lotion should not be used during pregnancy. Individual results may vary. Available by prescription only.

What is DUOBRII® Lotion?

DUOBRII (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, is a prescription medicine used on the skin (topical) to treat adults with plaque psoriasis. It is not known if DUOBRII Lotion is safe and effective in children.

Important Safety Information

  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.

What is the most important Information I should know about DUOBRII Lotion?

DUOBRII Lotion may cause birth defects if used during pregnancy. 

A negative pregnancy test must be obtained before females of child-bearing age start using DUOBRII Lotion and they must use effective birth control during treatment. Begin treatment during a normal menstrual period.

Stop using DUOBRII Lotion and tell your healthcare provider right away if you become pregnant while using DUOBRII Lotion.

Before you use DUOBRII Lotion, tell your healthcare provider if you:

  • have eczema or any other skin problems, including skin infections, which may need to be treated before using DUOBRII.
  • have diabetes, adrenal gland problems or liver problems.
  • are breastfeeding or plan to breastfeed. If you use DUOBRII and breastfeed, do not apply DUOBRII to your nipple area.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Especially tell your healthcare provider if you take corticosteroids by mouth or injection or use other skin products that contain corticosteroids.
  • Ask your healthcare provider for a list of medicines that may make your skin more sensitive to sunlight.

What should I avoid during treatment with DUOBRII?

  • To avoid a severe sunburn, avoid sunlight, including sunlamps and tanning beds, as much as possible, and use sunscreen, protective clothing and a hat while in sunlight. Talk to your healthcare provider if you get sunburn, and do not use DUOBRII Lotion until your sunburn is healed.
  • Avoid using DUOBRII on skin with eczema because it may cause severe irritation.

DUOBRII may cause side effects, including:

  • If too much DUOBRII passes through your skin it can cause adrenal glands to stop working
  • Cushing’s syndrome, a condition from too much exposure to the hormone cortisol
  • High blood sugar (hyperglycemia)
  • Effects of growth and weight in children
  • Skin irritation. If you get too much skin irritation at the site of application, your healthcare provider may tell you to interrupt or stop using DUOBRII or to use it less often.
  • Vision problems, including an increased chance of developing cataracts and glaucoma. Tell your healthcare provider about any vision problems during treatment.

The most common side effects of DUOBRII Lotion include: redness, itching, swelling, burning, stinging, application site pain, inflamed hair follicles (folliculitis), thinning of the skin (atrophy), peeling and rash.

To report SUSPECTED ADVERSE REACTIONS, contact Ortho Dermatologics at 1-800-321-4576 or FDA at 1-800-FDA-1088 or visit http://www.fda.gov/medwatch.

Please click here for full Prescribing Information, including Patient Information. DUO.0325.USA.20

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